During the 80’s, she participated in important young artist groups including the Enfatisti, in Bologna, and the Neo Conceptuals in Milano; the latter group's work culminated in the show Examples of New Italian Art at Riverside Studios, London in 1989. In the same year, Vittoria Chierici was nominated to represent Italy at the Tokyo international exhibition, 7 Artists.

In the late ‘90s, Chierici began to work on a new mixed media project comprising digital elaboration and painting, on the historical subject of The Battle of Anghiari, based on a lost mural by Leonardo Da Vinci. In 2000, a large work on canvas, Leonardo Scomparso, was commissioned by the City of Anghiari, Tuscany and permanently exhibited at the museum of Palazzo Marzocco. A large painting of the same subject, Anghiari Verde, is also permanently exhibited at Humanities Initiative, New York Univeristy.

Since the late nineties, Chierici had solo shows in Madrid, Spain and in Buenos Aires, Argentina. She exhibited her paintings and video projects in US, in New York and in Chicago. In 2006, she had a retrospective solo show of her paintings after Leonardo at the Italian Institute of Culture in Vancouver, Canada.

Since 2004, Chierici has begun a series of collaborations with American artists working in different art forms. Focusing on representing movement, since 2006, she has been collaborating as a set designer with choreographer Liz Gerring. In 2008, in collaboration with composer Eve Beglarian, Chierici has realized a media project - the video Wolf Chaser, edited by Phil Hartley, based on the general issue of energy and focusing on the feelings and imaginative responses engendered by industrial icons in the American landscape. In 2010, Chierici wrote an essay about New York artist Burt Barr for the Italian magazine, Dialoghi Internazionli. In 2011, Chierici commissioned to violinist and composer Ana Milosavljevic the music for the project, Luci in the Sk,y a digital film edited by film maker Yuko Takebe.

In 2010, invited by Corrado Levi and the art space in Milano, Lucie Fontaine, Chierici participated to the project, No Soul for Sale, at the Tate Modern Gallery in London. In January 2011, Lucie Fontaine organized a solo show, Allegro, ma non troppo: a retrospective of paintings by Vittoria Chierici, since the nineties. In spring 2012, Vittoria Chierici had her solo show, Variazioni, Riproposizioni, Modifiche at a new contemporay art space near Bologna, Le Torri dell'Acqua. The show was presented with a text by the art writer, Federico Sardella. In September 2012, Chierici has been invited to participate to the group show Estate, organized by Lucie Fontaine at Marianne Boesky gallery in New York City. Her new project Sailing away to Paint the Sea, has been exhibited in many venues and galleries, like the SUNY Maritime College in New York City, and at the renown cultural space, Frigoriferi Milanesi, Milano, March 2013.

Paintings and video installations by Vittoria Chierici have been shown in galleries and museums: Kunstmoderner Museum, Wien; Massimo Minini Gallery, Brescia; PAC, Contemporary Art Museum, Milano; Riverside Studios, London; Buades Gallery, Madrid; Museo Civico, Siena; Trevi Flash Art Museum; Italian Cultural Institute, New York; Esso Gallery, New York; Baryshnikov Art Center, New York; The TimesCenter, New York; The Warhol Museum, Pittsburgh, le Torri dell'Acqua, Budrio, Bologna; Centro Studi Dante Bighi, Copparo, Ferrara, Italy, Marianne Boesky, New York, Stephen B. Luce Library, SUNY Maritime College, New York.

Chierici’s works are in public collections: PAC, Contemporary Art Museum, Milano; GNAM, National Gallery of Modern and Contemporary Art, Rome; Museum of Modern Art, Arezzo; Palazzo del Marzocco, Anghiari, Italy;  MARTe Museo della Guerra, Rovereto, Trento; Carisbo Bank Foundation and Genius Bononiae, the new major public art collection of the City of Bologna; Republic of San Marino, state collection; Humanities Initiative, New York University, New York; La Vigna, Vicenza; public collection of the city of Budrio, Bologna; MAGI, museum of contemporary art, Pieve di Cento, Bologna; Italy; the prestigious library La Vigna, at Palazzo Brusarosco, Vicenza, Italy; the art collection of major Italian union, CGIL, Rome and Circolo della Rosa, the historical Italian feminists library and cultural center in Milano; MART, museum of modern and contemperare art of Trento and Rovereto; museum Ca' la Ghironda, Bologna.

She has been featured in essays and reviews by major Italian art writers and historians: Achille Bonito Oliva, Corrado Levi, Adachiara Zevi, Dario Trento, Federico Sardella, Francesco Matteo Cataluccio among the others; in art magazines and newspapers including Flash Art, Flash Art International, Tema Celeste, Domus, la Repubblica, Inventario.

Vittoria Chierici received her education in Art History at the University of Bologna, where she studied with Umberto Eco, Tomas Maldonado, Franco Donatoni and other Italian intellectuals who founded the new faculty, DAMS (Art, Music, and Performing Arts) and in New York, where, in the early 80's, she continued her studies in Art History at the UC Berkeley and Columbia, focusing on the migration of European avant garde artists to the US. She also studied Fine Arts at the School of Visual Arts and filmaking at the New York Film Academy.

In 2001, Chierici was awarded with Premio DAMS by the University of Bologna, for her achievements in the arts.

Vittoria Chierici has been assistant professor at the Milano Politecnico, Faculty of Design, from 2003 to 2006.

Since 2009, Chierici’s work is documented at the National Museum of Women in the Arts, In Washington DC.